'misfortune' originates from Old French, specifically the word 'mesfortune', where 'mes-' meant 'bad' and 'fortune' meant 'luck'.

'mesfortune' transformed into the Middle English word 'misfortune', and eventually became the modern English word 'misfortune'.

Initially, it meant 'bad luck or an unfortunate event', and this meaning has largely remained the same in modern usage.